BAX anticorps (pSer184) (FITC)
Aperçu rapide pour BAX anticorps (pSer184) (FITC) (ABIN682850)
Antigène
Voir toutes BAX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer184
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Cow,Sheep,Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184
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Isotype
- IgG
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Indications d'application
- FCM 1:20-100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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Autre désignation
- Bax
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Sujet
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Synonyms: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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Poids moléculaire
- 21kDa
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ID gène
- 581
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UniProt
- Q07812
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Pathways
- Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Antigène
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